Estimation of local anisotropy of plexiform bone: Comparison between depth sensing micro-indentation and Reference Point Indentation.

Investigation of Ultrastructural and Mechanical Properties of Rat Cortical Bone Using Micro-ct, Three- Point Bending Testing, and the Reference Point Indentation Technique By

Reference Point Indentation of Human Trabecular Bone Treated with Bisphosphonates for Varying Durations

OF THESIS REFERENCE POINT INDENTATION OF HUMAN TRABECULAR BONE TREATED WITH BISPHOSPHONATES FOR VARYING DURATIONS Reference point indentation (RPI), a novel form of micro-indentation, quantifies RPI material parameters which correlate with modulus, yield stress, strength, or toughness. Information linking bisphosphonate treatment length with the material properties of osteoporotic trabecular bo...

Prediction of viscoelastic and plastic properties of polymers using indentation

Indentation methodologies are gaining popularity as they provide means of local property estimation, utilize smaller sample sizes, and do not destroy specimens. Classically, indentation has been used to measure hardness and Young’s modulus [1], but researchers have also proposed ways of predicting stress–strain curves [2], yield strength [3], and fracture toughness [3]. Different indentation te...

A novel optical coherence tomography-based micro-indentation technique for mechanical characterization of hydrogels.

Depth-sensing micro-indentation has been well recognized as a powerful tool for characterizing mechanical properties of solid materials due to its non-destructive approach. Based on the depth-sensing principle, we have developed a new indentation method combined with a high-resolution imaging technique, optical coherence tomography, which can accurately measure the deformation of hydrogels unde...

Reference point indentation is not indicative of whole mouse bone measures of stress intensity fracture toughness

Bone fragility is a concern for aged and diseased bone. Measuring bone toughness and understanding fracture properties of the bone are critical for predicting fracture risk associated with age and disease and for preclinical testing of therapies. A reference point indentation technique (BioDent) has recently been developed to determine bone's resistance to fracture in a minimally invasive way b...